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Southwest Florida's Leading Experts in Regenerative Medicine

Discseel® Procedure

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Platelet Rich Plasma

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Stem Cell Therapy

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Prolotherapy

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Ozone Therapy

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Discseel® For Veterans

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Treating Spine, Joint Pain, and Neuropathy by Advanced Regenerative Medicine and Rehabilitation

Our pain treatment and rehabilitation clinic is centrally located in Estero Florida. Servicing Naples, Bonita Springs, Fort Myers, Cape Coral, Boca Raton, Coral Gables, Palm Beach, Fort Lauderdale & Miami Beach

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A non-surgical, whole person approach to pain management, specializing in regenerative treatment for chronic pain.

We are an Integrative Physical Medicine & Rehabilitation clinic located in Estero, FL. We offer a comprehensive team approach to help patients eliminate pain, restore function and achieve a state of health and wellness. By combining advanced regenerative medicine with rehabilitation, nutrition and integrative medicine,  we provide the best healing experience in Southwest Florida.

Patients From Around The World

Learn Why Doctor Sebastian is Leading
the Way in Regenerative Medicine:

Advanced Regenerative Therapy In Southwest Florida

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A Pain Relief Plan Just For You

Finding the right diagnosis is crucial to your treatment

We know that no two cases are the same – and we strive to ensure that each treatment plan is comprehensive and tailored to YOU. You’ll receive a comprehensive evaluation through the lenses of osteopathic, functional, regenerative and rehabilitative medicine, along with a detailed physical exam. We then can provide you with diagnostic imaging and labs (along with nerve studies and musculoskeletal ultrasound) in order to find the best course of treatment.

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Find Relief For Your Symptoms

Back pain relief, shoulder pain relief, knee pain relief…What are your symptoms?

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We are leaders in non-surgical relief for common problems and look at your pain from a holistic, comprehensive approach. We’re here to ensure you heal!

  • Neck Pain Treatment
  • Shoulder Pain Treatment
  • Elbow, Wrist & Hand Pain Treatment
  • Back and Spine Pain Treatment
  • Hip Pain Treatment
  • Knee Pain Treatment
  • Foot & Ankle Pain Treatment
  • Neuropathy Pain Treatment
  • Hypermobility Treatment
Schedule Your Consultation Today

Physical Therapy Compliments our Regenerative Treatment

Regaining your function with Physical Therapy

Therapeutic exercise, designed to improve the patient’s function and decrease disability, differs from traditional exercise as it takes into account the patient’s pain, injuries, and functional impairments. Therapeutic exercise helps to improve the patient’s functional condition and general health, and it is a key part of comprehensive treatment at our practice.

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Recent Blog Posts

PRP for Hair Restoration

Results after PRP for Hair Restoration PRP (Platelet Rich Plasma) is revolutionizing hair loss treatment that we are thrilled to be able to offer to ...
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Lateral Epicondylitis: Understanding and Treating Tennis Elbow for Long-Term Relief

If you’re experiencing persistent pain on the outside of the elbow, particularly when lifting, gripping, or typing, you may be dealing with a common condition ...
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Hip Bursitis: Causes, Symptoms, and Long-Term Treatment Options That Work

If you’re experiencing persistent pain on the outside of your hip—especially when walking, climbing stairs, or lying on your side—you may be suffering from hip ...
Read More →

PRP for Hair Restoration

Results after PRP for Hair Restoration PRP (Platelet Rich Plasma) is revolutionizing hair loss treatment that we are thrilled to be able to offer to ...
Read More →

Lateral Epicondylitis: Understanding and Treating Tennis Elbow for Long-Term Relief

If you’re experiencing persistent pain on the outside of the elbow, particularly when lifting, gripping, or typing, you may be dealing with a common condition ...
Read More →
Read More Blog Posts...

What Our Patients Say:

Integrative Rehab Medicine
Based on 152 reviews
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Egor Kelman
A true professional, Dr. Sebastian immediately identified my problem and recommended additional injections, which started working literally the next day. I felt initial relief in an area that had been in spasm for the past eight years.
Response from the owner:Thank you so much for sharing your experience! I’m thrilled to hear that you felt relief so quickly after your treatment. Our goal at Integrative Rehab Medicine in Estero, Florida is always to identify the true source of pain and deliver precise, non-surgical solutions that help our patients finally move and live without chronic muscle spasms or pain. It’s wonderful to see your body responding and healing after so many years. Thank you for trusting us with your care!
Maggie Castro
From the moment I walked in, I was treated with genuine warmth and respect. The entire team from the front desk staff to the nurses and Dr Floyd & Dr Sebastian were incredibly attentive and professional. They took the time to understand my concerns, explain the treatment plan thoroughly, and ensure all my questions were answered. I never felt rushed. I received calls & emails to check on my progress, ensuring that everything was going smoothly after my visit. I have done PRP & the discseel procedure. It has been a few months now and I am heeling well. Thank you so much to the entire Team!
Response from the owner:Thank you, Maggie, for your wonderful review and for trusting our team with your care! We’re so glad to hear that you felt supported throughout your PRP and Discseel treatments and that your healing is progressing well. At Integrative Rehab Medicine in Estero, Florida, our entire team — from the front desk to the nurses and physicians — is dedicated to providing personalized, compassionate, and regenerative care that helps each patient truly heal. We appreciate you sharing your experience and are honored to be part of your recovery journey!
Robert Long
I have not been here but I have seen Dr. Shiple in PA. He is one of the world's most flawless injectors! From PRP, Stellate Ganglion Block, Vagus Nerve Block, Hydrodissection etc...

He has gotten me out of a bedbound life.

He does even better when Bruce Hornsby is playing during the session 😁
Response from the owner:Thank you for sharing such kind words about Dr. Brian Shiple! He is indeed one of the most skilled and experienced regenerative injection specialists in the world, and we’re honored to have him on our team here at Integrative Rehab Medicine in Estero, Florida. It’s inspiring to hear how his advanced techniques—like PRP, Stellate Ganglion Block, Vagus Nerve Block, and ultrasound-guided hydrodissection—helped you reclaim your health and quality of life.
Patrick Gendreau
Dr. Sebastian and his team conducted a thorough review of my MRI, scheduled a Zoom consultation, and performed this transformative procedure—all within one month of my initial inquiry. The procedure was carried out at a state-of-the-art facility, which I would rate as exceptional.

Two months post-procedure, my lower back pain has improved by approximately 95%. Although I still have four months remaining in my recovery timeline, I already feel like a new person. I am now able to sleep comfortably, drive, and sit for extended periods without experiencing persistent discomfort or pain.

I highly recommend scheduling an MRI review to determine whether this procedure may be appropriate for individuals suffering from sciatica, degenerative disc disease, herniated discs, or other spinal issues. This technique represents a remarkable advancement in treatment.

— Patrick G
Response from the owner:Patrick, thank you for trusting us with your care here at our Estero FL clinic. We’re thrilled to hear how much relief from your back pain you’ve experienced just two months after your spine treatment. At Integrative Rehab Medicine, our team is committed to providing thorough diagnostics, from spinal MRI review to personalized in person and telehealth consultations, and delivering advanced regenerative treatments for sciatica, degenerative disc disease, herniated discs, and other spinal conditions. It’s wonderful to know our state-of-the-art facility and approach made such a difference for you. We truly appreciate your recommendation and look forward to supporting you throughout your recovery journey.
Ryan G
My wife and I traveled from Wisconsin to get my two herniated discs in lower back treated with ozone/prp. I could not be happier with how everything went. Dr. Sebastian and his team are wonderful. From the very beginning of sending in my mri results to after the procedure was so efficient and organized. Everyone at this clinic is very informative, professional and just the nicest people to be around. Especially for me being nervous having never had any back procedures done....they made it so much easier. I am looking forward to my continued healing. You have a raving fan in Wisconsin now and I'd only come to your clinic if I ever need future procedures! Thanks to everyone that helped me!
Response from the owner:Thank you so much for sharing your experience and for traveling all the way from Wisconsin to southwest Florida for your spinal treatments in our Estero clinic. We’re thrilled to hear that your ozone and PRP treatments for herniated discs in your lower back went smoothly and that our team helped you feel comfortable throughout the process. At Integrative Rehab Medicine, we strive to make every step — from MRI review to post-procedure care — efficient, professional, and reassuring. We’re grateful for your trust, excited to see your continued healing, and honored to have a raving fan in Wisconsin!
Alicia
Dr.Sebastian Klisiewicz, was very nice and helpful.He explained my diagnosis very clearly and help me to choose the best treatment for me. Thank you very much for all your help.
Response from the owner:Thank you, Alicia! We’re so glad to hear that you had a positive experience at our Estero clinic. At Integrative Rehab Medicine, we take pride in carefully diagnosing the root cause of pain and offering clear guidance on the best treatment options. It’s wonderful to know you felt supported throughout the process.
Francisca Santibanez
Excellent doctor.
He takes the time to explain the procedure, he does a thorough assessment and explains imaging.
Thank you doctor for making me feel better! I can finally do chores around my house, work without pain and finally enjoy little things in life, such as washing my car lol. I have no words to describe how good this procedure helped me. I also want to thank the staff, very nice people, and a great team!
Response from the owner:Francisca, we’re thrilled to hear that the Discseel® Procedure helped relieve your back pain without surgery. It’s wonderful that you had such a positive experience at our Estero clinic. We wish you continued healing and a smooth return to a fully active, pain-free life. 🙂
Sacha S.
After two severe car accidents in the span of 4yrs Dr. Sebastian has saved my life twice; literally. With a list of injuries so long ranging from disc herniations, bulging discs, nerve pain, cervical and lumbar instability, shoulder, knee, jaw, hip injuries and more. That would result in most people to just give up & most doctors to not have any patience for or solutions. With PRP & Prolotherapy he has been able to help me heal my body. I am truly blessed to have the absolute best doctor there is. With His amazing care, extensive knowledge and compassion he has given me my life back in more ways than I can express. Dr. Sebastian has a gift that most doctors don’t. You will meet many in your lifetime but he by far exceeds them all! Unsurpassable care in every way! From a life of absolute crippling pain to healing and hope. I would not be where I am without his exceptional care.
Response from the owner:Thank you so much for sharing your incredible journey. We are truly honored to have been part of your healing process here at our Estero clinic. It means the world to know that PRP and prolotherapy treatments have helped you recover from severe neck, back, and shoulder pain, along with your other injuries. Stories like yours remind us why we do what we do every day. We’re grateful for your trust and will always be here to support you in maintaining a healthy, active, and pain-free life.
larry wallen jr
They are very Professional & I am definitely improving in all of the areas which are being treated. Plus there is good follow up with a Physical Therapist & the Doctor.
Response from the owner:Larry, thank you for your kind words! We’re so glad to hear you’re improving with your treatments here at our Estero regenerative medicine clinic. At Integrative Rehab Medicine, our team — including the spine physician and physical therapist — is committed to providing professional, comprehensive care and strong follow-up to help patients overcome pain and return to active living.
P W
2 bouts of pt over 2 years couldn't resolve my back/ leg problem. 1st procedure at IRM: immediate relief within 24 hrs.
Response from the owner:Thank you for sharing your experience! We’re so glad that your first procedure here at our Estero clinic brought such quick relief. At Integrative Rehab Medicine, we specialize in accurately diagnosing the root cause of pain and providing targeted treatments to help patients return to an active, pain-free life.